Three-dimensional echocardiography has a number of significant benefits. It doesn't require plane positioning, geometric modeling, or suppositions about the shape of the chamber, and it measures a third dimension. With the advent of fully sampled matrix-array transducers, pyramidal volume datasets can now be measured from a single apical window. It is more accurate and dependable to measure volume directly. Since the middle of the 1990s, studies have verified real-time 3DE's capacity to precisely and repeatedly measure LV volumes, showing a strong correlation to other imaging modalities like cardiac magnetic resonance imaging and quantitative single-photon emission computer tomography. The first in vitro and in vivo studies using canine ventricles of known volume and different shapes revealed increased accuracy in measuring LV volume and function via 3DE compared to 2DE, especially with asymmetric shapes, such as LV aneurysms.

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